J Biol Chem. 1979 Jun 25;254(12):4954-6.

Phosphorylation of the 20,000-dalton light chain of myosin of intact arterial smooth muscle in rest and in contraction.

Abstract

The 20,000-dalton myosin light chain of intact pig carotid arteries was found to be rapidly labeled when the arterial muscle was incubated in physiological salt solution at 37 degrees C containing [32P]orthophosphate. Light chain phosphorylation in the intact muscle had a marked requirement for Ca2+ and was dependent upon the passive tension applied to the muscle. Norepinephrine- or KCl-induced contractures were associated with concomitant increases in light chain phosphorylation.

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Myosin light chain phosphorylation associated with contraction in arterial smooth muscle. [Am J Physiol. 1981]
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