Science. 1979 May 11;204(4393):624-6.

Hydroxylase cofactor activity in cerebrospinal fluid of normal subjects and patients with Parkinson's disease.

Lovenberg W, Levine RA, Robinson DS, Ebert M, Williams AC, Calne DB.

Abstract

A method for measuring hydroxylase cofactor activity in human cerebrospinal fluid is described. The hydroxylase cofactor content of cerebrsopinal fluid from Parkinsonian patients is approximately 50 percent that of normal subjects. A significant correlation between hydroxylase cofactor and the concentration of homovanillic acid in the cerebrospinal fluid was observed.

PMID:: 432666; [PubMed - indexed for MEDLINE]

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