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Int J Pept Protein Res. 1979 Feb;13(2):170-84.

An analysis of side-chain conformation in proteins.

Abstract

The crystal structures of a number of globular proteins are currently available. An analysis of the distribution of side-chains among different allowed conformations in these proteins has been carried out. The observed conformations of individual residues are discussed on the basis of well-known stereochemical criteria. The population distribution of side-chains in different allowed regions in conformational space can be explained largely on the basis of simple steric considerations. In addition to examining the conformational behaviour of individual residues, some population distributions of conformational angles of general interest involving groups of residues have also been analyzed.

PMID:
429093
[PubMed - indexed for MEDLINE]
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