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Biochem J. 1971 Jan;121(2):227-33.

Nature of the interaction of chondroitin 4-sulphate and chondroitin sulphate-proteoglycan with collagen.

Abstract

The electrostatic interaction of chondroitin sulphate and the chondroitin sulphate-proteoglycan with collagen was studied by chromatography of the glycosaminoglycan and the proteoglycan on a collagen gel. The observed binding between the macromolecules increased with decreasing pH and ionic strength, and was significant under physiological conditions. A study of the interaction between chondroitin sulphate and a preparation of soluble collagen, with a partition-equilibrium technique, afforded similar results.

PMID:
4256063
[PubMed - indexed for MEDLINE]
PMCID:
PMC1176559
Free PMC Article
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