Scand J Immunol. 1977;6(12):1351-6.

Idiotypy of measles virus nucleocapsid-specific IgGkappa antibody in serum and cerebrospinal fluid in subacute sclerosing panencephalitis.

Abstract

A gel-precipitating anti-idiotypic antiserum was prepared in a rabbit by immunization with measles virus-specific IgG isolated from the serum of a patient with subacute sclerosing pancencephalitis (SSPE). The idiotypic determinant was associated with an electrophoretically restricted and cathodally migrating IgGkappa protein in serum and cerebrospinal fluid (CSF) with antibody activity to measles nucleocapsids. The anti-idiotypic antiserum did not precipitate with other oligoclonal populations of measles-specific IgG in the patients serum or CSF, nor with serum or CSF from 4 other patients with SSPE and 10 patients with multiple sclerosis.

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Gel-precipitating measles virus antibodies in subacute sclerosing panencephalitis: relation to oligoclonal IgG proteins in the cerebrospinal fluid and serum, and the occurrence of two separate fractions of antibody to virus nucleocapsids. [Acta Pathol Microbiol Scand C....]
Gel-precipitating measles virus antibodies in subacute sclerosing panencephalitis: relation to oligoclonal IgG proteins in the cerebrospinal fluid and serum, and the occurrence of two separate fractions of antibody to virus nucleocapsids.
Vandvik B. Acta Pathol Microbiol Scand C. 1977 Oct; 85(5):324-32.
Oligoclonal measles virus-specific IgG antibodies isolated from cerebrospinal fluids, brain extracts, and sera from patients with subacute sclerosing panencephalitis and multiple sclerosis. [Scand J Immunol. 1976]
Oligoclonal measles virus-specific IgG antibodies isolated from cerebrospinal fluids, brain extracts, and sera from patients with subacute sclerosing panencephalitis and multiple sclerosis.
Vandvik B, Norrby E, Nordal HJ, Degré M. Scand J Immunol. 1976; 5(8):979-92.
Oligoclonal measles virus-specific IgG antibodies isolated from sera of patients with subacute sclerosing panencephalitis. [Scand J Immunol. 1977]
Oligoclonal measles virus-specific IgG antibodies isolated from sera of patients with subacute sclerosing panencephalitis.
Vandvik B. Scand J Immunol. 1977; 6(6-7):641-9.
Review Experimental subacute sclerosing panencephalitis (SSPE) in the hamster. [Adv Exp Med Biol. 1981]
Review Experimental subacute sclerosing panencephalitis (SSPE) in the hamster.
Johnson KP. Adv Exp Med Biol. 1981; 134:303-9.
Review [Clinical course and findings in and differential diagnosis of subacute sclerosing panencephalitis]. [Nihon Rinsho. 2007]
Review [Clinical course and findings in and differential diagnosis of subacute sclerosing panencephalitis].
Ichiyama T. Nihon Rinsho. 2007 Aug; 65(8):1481-2.

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Cited by 1 PubMed Central article

Oligoclonal immunoglobulins in subacute sclerosing panencephalitis and multiple sclerosis: a study of idiotypic determinants. [Clin Exp Immunol. 1979]
Oligoclonal immunoglobulins in subacute sclerosing panencephalitis and multiple sclerosis: a study of idiotypic determinants.
Ebers GC, Zabriskie JB, Kunkel HG. Clin Exp Immunol. 1979 Jan; 35(1):67-75.

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