MMW Munch Med Wochenschr. 1977 Apr 22;119(16):535-8.

[Effect of arginine ketoglutarate on the detoxifying capacity of the liver in cirrhosis of the liver (author's transl)].

[Article in German]

Abstract

According to the present studies it is shown that arginine ketoglutarate in sufficiently high dosage (3x3 g daily by mouth) produces a significant lowering of plasma ammonia and free serum phenols with a high-protein diet in patients with liver cirrhosis, compared to a previous day without this substance. The ammonia reduction can be explained by a significant increase in urea synthesis, measured by the urea nitrogen content of the 24-hour urine. The simultaneous lowering of pathologically raised serum levels of free phenols can be explained by an improved oxidative decomposition of these substances. No stimulation of insulin secretion worthy of note occurred after oral administration of 9 g arginine ketoglutarate.

PMID:: 405572; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Medical

Cirrhosis - MedlinePlus Health Information

Molecular Biology Databases

Supplemental Content

Related citations

[Influence of ornithin-alpha-ketoglutaric acid on fatmetabolism in patients with cirrhosis of the liver (author's transl)]. [Med Klin. 1976]
[Influence of ornithin-alpha-ketoglutaric acid on fatmetabolism in patients with cirrhosis of the liver (author's transl)].
Leinweber W, Goldberg P, Erb W. Med Klin. 1976 Jun 11; 71(24):1043-6.
Review Regulation of urea synthesis by diet protein and carbohydrate in normal man and in patients with cirrhosis. Relationship to glucagon and insulin. [Dan Med Bull. 1997]
Review Regulation of urea synthesis by diet protein and carbohydrate in normal man and in patients with cirrhosis. Relationship to glucagon and insulin.
Hamberg O. Dan Med Bull. 1997 Jun; 44(3):225-41.
Hepatic detoxification and hepatic function in chronic active hepatitis with and without cirrhosis. [Dig Dis Sci. 1988]
Hepatic detoxification and hepatic function in chronic active hepatitis with and without cirrhosis.
Müting D, Kalk JF, Fischer R, Wuzel H, Reikowski J. Dig Dis Sci. 1988 Jan; 33(1):41-6.
[On the effect of neomycin on blood ammonia, free amino acids and free phenols in serum and urine in liver cirrhosis]. [Med Welt. 1968]
[On the effect of neomycin on blood ammonia, free amino acids and free phenols in serum and urine in liver cirrhosis].
Müting D, Reikowski J, Reikowski H. Med Welt. 1968 May 11; 19:1235-9.
Review [Dietary problems in the treatment of portal hypertension with special reference to portacaval shunt]. [Med Klin. 1974]
Review [Dietary problems in the treatment of portal hypertension with special reference to portacaval shunt].
Müting D. Med Klin. 1974 Mar 15; 69(11):454-9.

See reviews... See all...

Chemical compound information

Arginine

MW: 174.20 g/mol

MF: C₆H₁₄N₄O₂

See 19 citations for this compound....

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

Recent activity

Clear Turn Off Turn On

[Effect of arginine ketoglutarate on the detoxifying capacity of the liver in ci...
[Effect of arginine ketoglutarate on the detoxifying capacity of the liver in cirrhosis of the liver (author's transl)].
MMW Munch Med Wochenschr. 1977 Apr 22 ;119(16):535-8.

PubMed
The impact of Vietnam service on heroin-addicted veterans.
The impact of Vietnam service on heroin-addicted veterans.
Am J Drug Alcohol Abuse. 1979 ;6(1):39-52.

PubMed
Autoradiographic studies of nicotinic acid utilization in human-mouse heterokary...
Autoradiographic studies of nicotinic acid utilization in human-mouse heterokaryons and inhibition of utilization in newly-formed hybrid cells.
J Cell Physiol. 1975 Dec ;86(3 Pt 1):439-52.

PubMed
Extracellular enzyme system utilized by the fungus Sporotrichum pulverulentum (C...
Extracellular enzyme system utilized by the fungus Sporotrichum pulverulentum (Chrysosporium lignorum) for the breakdown of cellulose. 3. Purification and physico-chemical characterization of an exo-1,4-beta-glucanase.
Eur J Biochem. 1975 Feb 3 ;51(1):213-8.

PubMed
Studies on bovine adrenal estrogen sulfotransferase. Inhibition and possible inv...
Studies on bovine adrenal estrogen sulfotransferase. Inhibition and possible involvement of adenine-estrogen stacking.
J Biol Chem. 1977 Oct 25 ;252(20):7214-20.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to:

[Effect of arginine ketoglutarate on the detoxifying capacity of the liver in cirrhosis of the liver (author's transl)].

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Medical

Molecular Biology Databases

Supplemental Content

Related citations

Chemical compound information

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information