Biochim Biophys Acta. 1985 Nov 8;832(1):46-51.

The primary structure of mitochondrial aspartate aminotransferase from human heart.

Martini F, Angelaccio S, Barra D, Pascarella S, Maras B, Doonan S, Bossa F.

Abstract

The complete amino acid sequence of the mitochondrial aspartate aminotransferase (L-aspartate:2-oxoglutarate aminotransferase, EC 2.6.1.1) from human heart has been determined based mainly on analysis of peptides obtained by digestion with trypsin and by chemical cleavage with cyanogen bromide. Comparison of the sequence with those of the isotopic isoenzymes from pig, rat and chicken showed 27, 29 and 55 differences, respectively, out of a total of 401 amino acid residues. Evidence for structural microheterogeneity at position 317 has also been obtained.

PMID:: 4052435; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Elsevier Science

Supplemental Content

Save items

Related citations in PubMed

The complete amino acid sequence of mitochondrial glutamic oxaloacetic transaminase from rat liver. [J Biochem. 1981]
The complete amino acid sequence of mitochondrial glutamic oxaloacetic transaminase from rat liver.
Huynh QK, Sakakibara R, Watanabe T, Wada H. J Biochem. 1981 Sep; 90(3):863-75.
The covalent structure of mitochondrial aspartate aminotransferase from chicken. Identification of segments of the polypeptide chain invariant specifically in the mitochondrial isoenzyme. [J Biol Chem. 1983]
The covalent structure of mitochondrial aspartate aminotransferase from chicken. Identification of segments of the polypeptide chain invariant specifically in the mitochondrial isoenzyme.
Graf-Hausner U, Wilson KJ, Christen P. J Biol Chem. 1983 Jul 25; 258(14):8813-26.
The complete amino acid sequence of aspartate aminotransferase from Escherichia coli: sequence comparison with pig isoenzymes. [Biochem Biophys Res Commun. 1984]
The complete amino acid sequence of aspartate aminotransferase from Escherichia coli: sequence comparison with pig isoenzymes.
Kondo K, Wakabayashi S, Yagi T, Kagamiyama H. Biochem Biophys Res Commun. 1984 Jul 18; 122(1):62-7.
Review Evolutionary and biosynthetic aspects of aspartate aminotransferase isoenzymes and other aminotransferases. [Ann N Y Acad Sci. 1990]
Review Evolutionary and biosynthetic aspects of aspartate aminotransferase isoenzymes and other aminotransferases.
Christen P, Jaussi R, Juretić N, Mehta PK, Hale TI, Ziak M. Ann N Y Acad Sci. 1990; 585:331-8.
Review Structural and genetic relationships between cytosolic and mitochondrial isoenzymes. [Int J Biochem. 1984]
Review Structural and genetic relationships between cytosolic and mitochondrial isoenzymes.
Doonan S, Barra D, Bossa F. Int J Biochem. 1984; 16(12):1193-9.

See reviews... See all...

Cited by 3 PubMed Central articles

Review Structure, expression, and function of kynurenine aminotransferases in human and rodent brains. [Cell Mol Life Sci. 2010]
Review Structure, expression, and function of kynurenine aminotransferases in human and rodent brains.
Han Q, Cai T, Tagle DA, Li J. Cell Mol Life Sci. 2010 Feb; 67(3):353-68. Epub 2009 Oct 15.
Rapid purification and thermostability of the cytoplasmic aspartate aminotransferase from carrot suspension cultures. [Plant Physiol. 1991]
Rapid purification and thermostability of the cytoplasmic aspartate aminotransferase from carrot suspension cultures.
Turano FJ, Wilson BJ, Matthews BF. Plant Physiol. 1991 Oct; 97(2):606-12.
The amino acid sequence of cytosolic aspartate aminotransferase from human liver. [Biochem J. 1990]
The amino acid sequence of cytosolic aspartate aminotransferase from human liver.
Doyle JM, Schininà ME, Bossa F, Doonan S. Biochem J. 1990 Sep 15; 270(3):651-7.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
BioSystems
Pathways and biological systems (BioSystems) that cite the current articles. Citations are from the BioSystems source databases (KEGG and BioCyc).
Compound
PubChem chemical compound records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records. Multiple substance records may contribute to the PubChem compound record.
Gene
Gene records that cite the current articles. Citations in Gene are added manually by NCBI or imported from outside public resources.
HomoloGene
HomoloGene clusters of homologous genes and sequences that cite the current articles. These are references on the Gene and sequence records in the HomoloGene entry.
Nucleotide (RefSeq)
NCBI nucleotide Reference Sequences (RefSeqs) that are cited in the current articles, included in the corresponding Gene Reference into Function, or that include the PubMed articles as references.
Nucleotide (Weighted)
Nucleotide records associated with the current articles through the Gene database. These are the related sequences on the Gene record that are added manually by NCBI.
Protein (RefSeq)
NCBI protein Reference Sequences (RefSeqs) that are cited in the current articles, included in the corresponding Gene Reference into Function, or that include the PubMed articles as references.
Protein (Weighted)
Protein records associated with the current articles through related Gene database records. These are the related sequences on the Gene record that are added manually by NCBI.
Substance
PubChem chemical substance records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Taxonomy via GenBank
Taxonomy records associated with the current articles through taxonomic information on related molecular database records (Nucleotide, Protein, Gene, SNP, Structure).
UniGene
UniGene clusters of expressed sequences that are associated with the current articles through references on the clustered sequence records and related Gene records.
Protein
Protein translation features of primary database (GenBank) nucleotide records reported in the current articles as well as Reference Sequences (RefSeqs) that include the articles as references.
GEO Profiles
Gene Expression Omnibus (GEO) Profiles of molecular abundance data. The current articles are references on the Gene record associated with the GEO profile.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

The primary structure of mitochondrial aspartate aminotransferase from human hea...
The primary structure of mitochondrial aspartate aminotransferase from human heart.
Biochim Biophys Acta. 1985 Nov 8 ;832(1):46-51.

PubMed
Anaesthesia and progressive muscular dystrophy.
Anaesthesia and progressive muscular dystrophy.
Br J Anaesth. 1985 Nov ;57(11):1113-8.

PubMed
Efficiency and effectiveness.
Efficiency and effectiveness.
Arch Emerg Med. 1985 Sep ;2(3):109-12.

PubMed
Differences in hair roots among children with differing nutritional status and o...
Differences in hair roots among children with differing nutritional status and of different ethnic origins. Clinical investigators should first establish their own normal standards for each ethnic group being studied.
Clin Pediatr (Phila). 1977 Jul ;16(7):599-600.

PubMed
The vertical wheeler: a device for ambulation in cerebral palsy.
The vertical wheeler: a device for ambulation in cerebral palsy.
Arch Phys Med Rehabil. 1985 Oct ;66(10):717-20.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: