J Biol Chem. 1985 Oct 5;260(22):12219-23.

Structure of a novel phosphoglycolipid from Deinococcus radiodurans.

Abstract

The chemical structure of a major phosphoglycolipid from Deinococcus radiodurans has been shown to be 2'-O-(1,2-diacyl-sn-glycero-3-phospho)-3'-O-(alpha-galactosyl)-N-D-gl yceroyl alkylamine. By infrared spectroscopy, the lipid was shown to contain both carbonyl ester and amide linkages. Chemical analysis demonstrated a molar ratio of fatty acid, carbohydrate, and phosphorus of 2:1:1. The lipid was shown to contain an sn-3-phosphatidic acid backbone by digestion with phospholipase A2. Phosphodiester bond cleavage of the lipid with hydrofluoric acid liberated a component which contained galactose, glyceric acid, and alkylamines. Using NMR and permethylation/hydrolysis procedures, galactose was shown to be linked alpha-glycosidically to the 3-O-position of glyceric acid.

PMID:: 4044593; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Research Support, Non-U.S. Gov't

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

HighWire Press - PDF

Supplemental Content

Save items

Related citations in PubMed

Structure of a novel glucosamine-containing phosphoglycolipid from Deinococcus radiodurans. [J Biol Chem. 1989]
Structure of a novel glucosamine-containing phosphoglycolipid from Deinococcus radiodurans.
Huang Y, Anderson R. J Biol Chem. 1989 Nov 5; 264(31):18667-72.
On the relationship between glycerophosphoglycolipids and lipoteichoic acids of gram-positive bacteria. III. Di(glycerophospho)-acylkojibiosyldiacylglycerol and related compounds from Streptococcus lactis NCDO 712. [Biochim Biophys Acta. 1978]
On the relationship between glycerophosphoglycolipids and lipoteichoic acids of gram-positive bacteria. III. Di(glycerophospho)-acylkojibiosyldiacylglycerol and related compounds from Streptococcus lactis NCDO 712.
Laine RA, Fischer W. Biochim Biophys Acta. 1978 May 25; 529(2):250-62.
Phosphatidylglyceroylalkylamine, a novel phosphoglycolipid precursor in Deinococcus radiodurans. [J Bacteriol. 1991]
Phosphatidylglyceroylalkylamine, a novel phosphoglycolipid precursor in Deinococcus radiodurans.
Huang Y, Anderson R. J Bacteriol. 1991 Jan; 173(2):457-62.
Archaea contain a novel diether phosphoglycolipid with a polar head group identical to the conserved core of eucaryal glycosyl phosphatidylinositol. [J Biol Chem. 1992]
Archaea contain a novel diether phosphoglycolipid with a polar head group identical to the conserved core of eucaryal glycosyl phosphatidylinositol.
Nishihara M, Utagawa M, Akutsu H, Koga Y. J Biol Chem. 1992 Jun 25; 267(18):12432-5.
Review Widespread occurrence of 2-acetylthiazole-4-carboxylic acid in biological material. [Experientia. 1990]
Review Widespread occurrence of 2-acetylthiazole-4-carboxylic acid in biological material.
White RH. Experientia. 1990 Mar 15; 46(3):274-6.

See reviews... See all...

Cited by 6 PubMed Central articles

Review Oxidative stress resistance in Deinococcus radiodurans. [Microbiol Mol Biol Rev. 2011]
Review Oxidative stress resistance in Deinococcus radiodurans.
Slade D, Radman M. Microbiol Mol Biol Rev. 2011 Mar; 75(1):133-91.
Complete genome sequence of Meiothermus ruber type strain (21). [Stand Genomic Sci. 2010]
Complete genome sequence of Meiothermus ruber type strain (21).
Tindall BJ, Sikorski J, Lucas S, Goltsman E, Copeland A, Glavina Del Rio T, Nolan M, Tice H, Cheng JF, Han C, et al. Stand Genomic Sci. 2010 Jul 29; 3(1):26-36. Epub 2010 Jul 29.
Review Genome of the extremely radiation-resistant bacterium Deinococcus radiodurans viewed from the perspective of comparative genomics. [Microbiol Mol Biol Rev. 2001]
Review Genome of the extremely radiation-resistant bacterium Deinococcus radiodurans viewed from the perspective of comparative genomics.
Makarova KS, Aravind L, Wolf YI, Tatusov RL, Minton KW, Koonin EV, Daly MJ. Microbiol Mol Biol Rev. 2001 Mar; 65(1):44-79.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound
PubChem chemical compound records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records. Multiple substance records may contribute to the PubChem compound record.
Substance
PubChem chemical substance records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Structure of a novel phosphoglycolipid from Deinococcus radiodurans.
Structure of a novel phosphoglycolipid from Deinococcus radiodurans.
J Biol Chem. 1985 Oct 5 ;260(22):12219-23.

PubMed
Metrizamide myelography risk factors: a pseudopsychiatric case presentation.
Metrizamide myelography risk factors: a pseudopsychiatric case presentation.
J Clin Psychiatry. 1985 Oct ;46(10):439-40.

PubMed
Rapid method for the diagnosis of partial adenine phosphoribosyltransferase defi...
Rapid method for the diagnosis of partial adenine phosphoribosyltransferase deficiencies causing 2,8-dihydroxyadenine urolithiasis.
Hum Genet. 1985 ;71(2):167-70.

PubMed
A comparative study of procedures for sheep erythrocyte-human-T-lymphocyte roset...
A comparative study of procedures for sheep erythrocyte-human-T-lymphocyte rosette formation.
J Immunol Methods. 1977 ;15(3):239-45.

PubMed
The influence of body fat distribution on the incidence of diabetes mellitus. 13...
The influence of body fat distribution on the incidence of diabetes mellitus. 13.5 years of follow-up of the participants in the study of men born in 1913.
Diabetes. 1985 Oct ;34(10):1055-8.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: