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1: Trans R Soc Trop Med Hyg. 1985;79(2):256-9.Links

The radioallergosorbent test (RAST) for the serological diagnosis of human anisakiasis.

Desowitz RS, Raybourne RB, Ishikura H, Kliks MM.

The serum of patients with parasitologically confirmed and one patient with a clinically presumptive case of anisakiasis were tested by the radioallergosorbent test (RAST) and counter-electrophoresis (CEP) for IgE and IgG antibodies, respectively, using antigens prepared from larval (L3) stage Anisakis simplex and larval (L2) stage Toxocara canis. All sera were RAST-positive to the A. simplex antigen and RAST-negative to the T. canis antigen. All sera were CEP-negative to both antigens. The presence of a specific IgE antibody suggests that the RAST could serve as a useful technique for the serodiagnosis of anisakiasis in man.

PMID: 4039859 [PubMed - indexed for MEDLINE]