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The phenyl- and biphenyl-quinolizidines of in-vitro-grown Heimia salicifolia.
Under the conditions delineated in this paper, alkaloid synthesis was not detectable in heterotrophic callus and suspension cultures of Heimia salicifolia. However, in vitro-grown shoots are active in alkaloid biosynthesis, yielding the biphenylquinolizidine lactones vertine (1), lytrine (5), and lyfoline (7), the ester alkaloids demethoxyabresoline (14) and epidemethoxylabresoline (11), the phenylquinolizidinols demethyllasubine-I (10) and demethyllasubine-II (12), and several minor alkaloids that had not been previously shown to occur in H. salicifolia.
PMID: 4009185 [PubMed - indexed for MEDLINE]
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