L-155,175: a new antiparasitic macrolide. Fermentation, isolation and structure

M A Goetz; P A McCormick; R L Monaghan; D A Ostlind; O D Hensens; J M Liesch; G Albers-Schonberg

doi:10.7164/antibiotics.38.161

L-155,175: a new antiparasitic macrolide. Fermentation, isolation and structure

J Antibiot (Tokyo). 1985 Feb;38(2):161-8. doi: 10.7164/antibiotics.38.161.

Authors

M A Goetz, P A McCormick, R L Monaghan, D A Ostlind, O D Hensens, J M Liesch, G Albers-Schonberg

PMID: 3997663
DOI: 10.7164/antibiotics.38.161

Abstract

A new antiparasitic macrolide, L-155,175, produced by a strain of Streptomyces hygroscopicus, has been isolated; its structure was determined by physico-chemical means. It is active against the tapeworm Hymenolepis diminuta in rats.

MeSH terms

Antiprotozoal Agents / analysis
Antiprotozoal Agents / isolation & purification*
Chemical Phenomena
Chemistry
Culture Media / analysis
Fermentation
Magnetic Resonance Spectroscopy
Soil Microbiology
Solvents
Streptomyces / analysis
Streptomyces / metabolism
Structure-Activity Relationship

Substances

Antiprotozoal Agents
Culture Media
Solvents