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    J Steroid Biochem. 1985 Mar;22(3):435-6.

    A new defect in the peripheral conversion of cortisone to cortisol.

    Abstract

    A steroid disorder is described in two sisters, aged 13 and 17 years, in which the metabolism of cortisol results almost exclusively in urinary excretion of tetrahydro-cortisone (11-keto) derivatives. The evidence implies the existence of a deficiency in the peripheral enzymatic conversion of cortisone to cortisol.

    PMID:
    3990293
    [PubMed - indexed for MEDLINE]

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