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1: Pharmacol Biochem Behav. 1985 Feb;22(2):347-8.Click here to read Links

Efficacy of trazodone as an anti obsessional agent.

Eight patients with chronic Obsessive-Compulsive Neurosis were subjected to Trazodone, an antidepressant acting on the serotinergic system. After 4 weeks of treatment, 6 showed significant reduction in the obsessional symptoms which was sustained after a 6-week follow-up. The 2 patients who did not show improvement had a significantly higher trait score than the others on psychometric ratings.

PMID: 3983224 [PubMed - indexed for MEDLINE]

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    Trazodone is used to treat depression. Trazodone is in a class of medications called serotonin modulators. It works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balan...