Scand J Clin Lab Invest. 1979 Dec;39(8):759-64.

Erythrocyte superoxide dismutase deficiency in Fanconi's anaemia established by two independent methods of assay.

Joenje H, Frants RR, Arwert F, de Bruin GJ, Kostense PJ, van de Kamp JJ, de Koning J, Eriksson AW.

Abstract

Erythrocyte superoxide dismutase (SOD; E.C.1.15.1.1) levels were quantitated in human haemolysates, both by an immunological technique and by an activity assay. The erythrocyte SOD activity level in a group of seven Fanconi's anaemia patients was significantly decreased (27%, on the average) compared to a control group of nineteen healthy individuals. The fact that both the activity per antigenic unit and the electrophoretic mobility of the erythrocyte SOD was normal indicates that the deficiency in these Fanconi's anaemia patients is most probably not due to a mutation in the structural gene for the enzyme but more likely due to a disturbed mechanism regulating the SOD level in the erythrocyte.

PMID:: 394299; [PubMed - indexed for MEDLINE]

MeSH Terms, Substances

MeSH Terms

Substances

Superoxide Dismutase

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Medical

Aplastic Anemia - MedlinePlus Health Information

Supplemental Content

Save items

Related citations in PubMed

Decreased superoxide dismutase activity of erythrocytes and leukocytes in Fanconi's anemia. [Acta Haematol. 1984]
Decreased superoxide dismutase activity of erythrocytes and leukocytes in Fanconi's anemia.
Yoshimitsu K, Kobayashi Y, Usui T. Acta Haematol. 1984; 72(3):208-10.
Erythrocyte superoxide dismutase activity in Fanconi's anaemia. [Clin Sci (Lond). 1980]
Erythrocyte superoxide dismutase activity in Fanconi's anaemia.
Okahata S, Kobayashi Y, Usui T. Clin Sci (Lond). 1980 Feb; 58(2):173-5.
Erythrocyte superoxide-dismutase deficiency in Fanconi's anaemia. [Lancet. 1978]
Erythrocyte superoxide-dismutase deficiency in Fanconi's anaemia.
Joenje H, Eriksson AW, Frants RR, Arwert F, Houwen B. Lancet. 1978 Jan 28; 1(8057):204.
Review Fanconi's anemia as a nature's evolutionary experiment on carcinogenesis. [Tohoku J Exp Med. 1987]
Review Fanconi's anemia as a nature's evolutionary experiment on carcinogenesis.
Okuyama S, Mishina H. Tohoku J Exp Med. 1987 Oct; 153(2):87-102.
Review Chromatographic and electrophoretic methods for analysis of superoxide dismutases. [J Chromatogr B Biomed Appl. 1996]
Review Chromatographic and electrophoretic methods for analysis of superoxide dismutases.
Michalski WP. J Chromatogr B Biomed Appl. 1996 Sep 20; 684(1-2):59-75.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Gene (OMIM)
Gene records associated with Online Mendelian Inheritance in Man (OMIM) records that cite the current articles in their reference lists.
Nucleotide (Weighted)
Nucleotide records associated with the current articles through the Gene database. These are the related sequences on the Gene record that are added manually by NCBI.
OMIM (calculated)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as references in the light bulb links within or in the citations at the end of the OMIM record. The references available through the light bulb link are collected using the PubMed related articles algorithm to identify records with similar terminology to the OMIM record.
OMIM (cited)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as reference cited at the end of the OMIM record.
Protein (Weighted)
Protein records associated with the current articles through related Gene database records. These are the related sequences on the Gene record that are added manually by NCBI.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

Recent activity

Clear Turn Off Turn On

Erythrocyte superoxide dismutase deficiency in Fanconi's anaemia established by ...
Erythrocyte superoxide dismutase deficiency in Fanconi's anaemia established by two independent methods of assay.
Scand J Clin Lab Invest. 1979 Dec ;39(8):759-64.

PubMed
Evaluating the effectiveness of a process medical audit in a teaching general ho...
Evaluating the effectiveness of a process medical audit in a teaching general hospital.
CMAJ. 1986 Feb 15 ;134(4):350-2.

PubMed
Influence of factors before and during medical school on choice of psychiatry as...
Influence of factors before and during medical school on choice of psychiatry as a specialty.
Am J Psychiatry. 1986 Jan ;143(1):77-80.

PubMed
Posterior sagittal approach for the correction of anorectal malformations.
Posterior sagittal approach for the correction of anorectal malformations.
Adv Surg. 1986 ;19:69-100.

PubMed
The impact of the acquired immunodeficiency syndrome on medical residency traini...
The impact of the acquired immunodeficiency syndrome on medical residency training.
N Engl J Med. 1986 Jan 16 ;314(3):177-80.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: