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    Science. 1985 Jun 28;228(4707):1547-9.

    Localization of the gene encoding the human interleukin-2 receptor on chromosome 10.

    Leonard WJ, Donlon TA, Lebo RV, Greene WC.

    The human interleukin-2 receptor is an inducible growth factor receptor present on the surface of activated T lymphocytes. The receptor is required for a normal T-cell immune response. High-resolution fluorescence-activated chromosome sorting and DNA spot-blot analysis with complementary DNA's for the interleukin-2 receptor indicated that the receptor gene was located on chromosome 9, 10, 11, or 12. In situ hybridization studies showed that the interleukin-2 receptor gene is on the short arm of chromosome 10, p14----15.

    PMID: 3925551 [PubMed - indexed for MEDLINE]

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