Br Med J (Clin Res Ed). 1985 Feb 2;290(6465):347-9.

Use of anti-inflammatory drugs by patients admitted with small or large bowel perforations and haemorrhage.

Abstract

The intake of anti-inflammatory drugs by 268 patients with colonic or small bowel perforation or haemorrhage was compared with that by a group of patients, matched for age and sex, with uncomplicated lower bowel disease. Patients with perforation or haemorrhage were more than twice as likely to be takers of anti-inflammatory drugs, but no association was detected with the intake of other types of drugs, particularly cardiovascular drugs. The association between complicated lower bowel disease and intake of anti-inflammatory drugs may be causal.

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