Clin Ther. 1985;7(6):699-703.

A controlled trial of amitriptyline and cianopramine in major depression.

Abstract

The therapeutic efficacy and adverse effects of amitriptyline and cianopramine were compared in a double-blind, randomized, flexible-dose trial in 40 patients with major depressive episodes. The two drugs were equally effective in reducing scores on the Hamilton Psychiatric Rating Scale for Depression and on a global scale. Both drugs were associated with significant adverse effects. Fewer adverse effects were associated with cianopramine, however, which lacks antimuscarinic activity.

PMID:: 3907842; [PubMed - indexed for MEDLINE]

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A controlled trial of amitriptyline and cianopramine in major depression.
A controlled trial of amitriptyline and cianopramine in major depression.
Clin Ther. 1985 ;7(6):699-703.

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A controlled trial of amitriptyline and cianopramine in major depression.

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