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Arch Dis Child. 1985 Aug;60(8):710-3.

Prevention of intraventricular haemorrhage by fresh frozen plasma.

Abstract

Seventy three preterm infants weighing less than 1500 g or less than 32 weeks' gestation, or both, were allocated randomly to treatment (fresh frozen plasma 10 ml/kg on admission and at 24 hours of age) or control groups. Fifteen (41%) out of 37 control patients sustained intraventricular haemorrhage compared with five (14%) of 36 patients receiving treatment (X2 = 5.24, P = 0.022). No difference was found in coagulation factors measured at birth or at 48 hours of age in both groups. Fresh frozen plasma appears to have a beneficial effect in the prevention of intraventricular haemorrhage.

PMID:
3899020
[PubMed - indexed for MEDLINE]
PMCID:
PMC1777434
Free PMC Article
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