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    Am J Hum Genet. 1985 Sep;37(5):868-72.

    Chromosomal localization of the human alpha 1-antitrypsin gene (PI) to 14q31-32.

    Abstract

    In situ hybridization of a recombinant cDNA probe containing the human alpha 1-antitrypsin gene to metaphase chromosomes demonstrated significant hybridization to chromosomal segment 14q31-32. A high percentage of cells analyzed (31%) displayed labeling on chromosome 14. Of all labeled sites on chromosome 14, 60% were found on segment 14q31-32. These results refine the previous assignment of the human alpha 1-antitrypsin gene to segment 14q24.1-32.1.

    PMID:
    3876766
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC1684682
    Free PMC Article

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