J Obstet Gynecol Neonatal Nurs. 1985 Nov-Dec;14(6):468-70.

Effects of in utero exposure to DES on male progeny.

Abstract

Diethylstilbestrol (DES) was prescribed for almost 30 years by physicians who believed the nonsteroidal synthetic estrogen was beneficial in both the treatment of threatened abortions and the prevention of spontaneous abortions. Toxemia, premature delivery, postmaturity, and stillbirth were said to be significantly reduced in patients who were treated with DES. The consequences of in utero exposure to DES on female progeny have been widely publicized. However, male progeny also suffer the effects of in utero exposure to DES. These effects include epididymal cysts, small penile size, and cryptorchidism. Altered reproductive capacity is suggested by diminished sperm counts and sperm penetration assays.

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Review [Fertility disorders attributable to the use of diethylstilbestrol during intrauterine life]. [Rev Fr Gynecol Obstet. 1984]
Review [Fertility disorders attributable to the use of diethylstilbestrol during intrauterine life].
Drapier E. Rev Fr Gynecol Obstet. 1984 Apr; 79(4):297-300, 303-5.
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Cited by 1 PubMed Central article

Estrogen receptor-α mediates diethylstilbestrol-induced feminization of the seminal vesicle in male mice. [Environ Health Perspect. 2012]
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Walker VR, Jefferson WN, Couse JF, Korach KS. Environ Health Perspect. 2012 Apr; 120(4):560-5. Epub 2012 Jan 24.

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Effects of in utero exposure to DES on male progeny.
Effects of in utero exposure to DES on male progeny.
J Obstet Gynecol Neonatal Nurs. 1985 Nov-Dec ;14(6):468-70.

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Effects of in utero exposure to DES on male progeny.

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