Harnessing the power of goat milk-derived extracellular vesicles for medical breakthroughs: A review

Int J Biol Macromol. 2024 Mar;262(Pt 2):130044. doi: 10.1016/j.ijbiomac.2024.130044. Epub 2024 Feb 8.

Abstract

Research into goat milk-derived extracellular vesicles (GMVs) has grown in popularity in recent years owing to their potential uses in several sectors, including medicine. GMVs are tiny, lipid-bound structures that cells secrete and use to transport bioactive substances like proteins, lipids, and nucleic acids. They may be extracted from different body fluids, including blood, urine, and milk, and have been found to play crucial roles in cell-to-cell communication. GMVs are a promising field of study with applications in preventing and treating various disorders. Their immune-modulating properties, for instance, have been investigated, and they have shown promise in treating autoimmune illnesses and cancer. They may be loaded with therapeutic compounds and directed to particular cells or tissues, but they have also been studied for their potential use as drug-delivery vehicles. Goat milk extracellular vesicles are an intriguing study topic with many possible benefits. Although more study is required to thoroughly understand their functioning and prospective applications, they provide a promising path for creating novel medical treatments and technology.

Keywords: Goat milk-derived extracellular vesicles; Imaging; Immunomodulatory.

Publication types

  • Review

MeSH terms

  • Animals
  • Drug Delivery Systems
  • Extracellular Vesicles* / metabolism
  • Goats
  • Milk / chemistry
  • Neoplasms* / metabolism