Microwave ablation for recurrent primary hyperparathyroidism in four patients with multiple endocrine neoplasia type 1: a case series report

Int J Hyperthermia. 2024;41(1):2308056. doi: 10.1080/02656736.2024.2308056. Epub 2024 Feb 5.

Abstract

Multiple endocrine neoplasia type 1 (MEN1), a rare tumor syndrome, is inherited in an autosomal dominant pattern, mainly manifested as primary hyperparathyroidism (PHPT). Surgery is preferred for patients with MEN1 and PHPT. Thermal ablation has been widely applied for PHPT but rarely for postoperative recurrent PHPT in MEN1 patients. Based on a series of cases, we aimed to investigate the clinical efficacy and safety of ultrasound-guided percutaneous microwave ablation in the treatment of MEN1 patients with postoperative recurrence of PHPT.

Keywords: Microwave ablation; case series report; multiple endocrine neoplasia; primary hyperparathyroidism; recurrence.

Publication types

  • Case Reports

MeSH terms

  • Humans
  • Hyperparathyroidism, Primary* / diagnostic imaging
  • Hyperparathyroidism, Primary* / surgery
  • Microwaves / therapeutic use
  • Multiple Endocrine Neoplasia Type 1* / complications
  • Multiple Endocrine Neoplasia Type 1* / surgery
  • Parathyroidectomy
  • Treatment Outcome