Sinus of Valsalva aneurysm associated with multiple conotruncal congenital malformations

Hum Pathol. 1987 Jan;18(1):96-9. doi: 10.1016/s0046-8177(87)80202-2.

Abstract

A case of rupture of a sinus of Valsalva aneurysm in a middle-aged woman with an unusual assortment of associated conotruncal and other cardiac anomalies is reported. The anomalies included bicuspid aortic valve, aortic sinus aneurysm (ruptured), quadricuspid pulmonic valve, membranous coarctation of the aorta, subclavian and common carotid arteries arising directly from aorta, and atrial septal defect. Excluding the atrial septal defect, these anomalies may be explained by a single embryologic event affecting conobulbar septation and aortic arch development occurring at the level of neural crest development.

Publication types

  • Case Reports

MeSH terms

  • Aortic Rupture / complications*
  • Female
  • Heart Defects, Congenital / complications*
  • Heart Defects, Congenital / pathology
  • Humans
  • Middle Aged
  • Sinus of Valsalva / pathology*