A novel case of acute glomerulonephritis with concurrent acute non-rheumatic myocarditis following group a streptococcal infection

J Int Med Res. 2023 Dec;51(12):3000605231173275. doi: 10.1177/03000605231173275.

Abstract

Streptococcal infection is a common cause of acute glomerulonephritis. Cardiac damage associated with streptococcal infection commonly occurs in acute rheumatic fever. However, cases of acute non-rheumatic streptococcal myocarditis have been reported in recent years. We report a novel case of concurrent acute glomerulonephritis and non-rheumatic myocarditis following streptococcal infection. A good prognosis was achieved with antibiotic and immunosuppressive therapy, indicating that Streptococcus causes cardiorenal syndrome type 5 via an immune-mediated response. A better understanding of post-streptococcal cardiorenal syndrome is warranted to enable the early diagnosis and treatment of affected patients.

Keywords: Group A streptococcus; acute non-rheumatic streptococcal myocarditis; cardiac damage; cardiorenal syndrome; immunosuppressive therapy; post-streptococcal glomerulonephritis.

MeSH terms

  • Acute Disease
  • Cardio-Renal Syndrome* / complications
  • Glomerulonephritis* / complications
  • Glomerulonephritis* / diagnosis
  • Humans
  • Myocarditis* / complications
  • Rheumatic Heart Disease* / complications
  • Streptococcal Infections* / complications
  • Streptococcal Infections* / diagnosis
  • Streptococcus pyogenes