Safety Assessment of Alkyl Sultaines as Used in Cosmetics

Int J Toxicol. 2024 Feb;43(1_suppl):30S-49S. doi: 10.1177/10915818231221791. Epub 2023 Dec 21.

Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 13 alkyl sultaines, which are most frequently reported to function in cosmetics as antistatic agents, surfactants, and skin and hair conditioning agents. The Panel reviewed the available data to determine the safety of these ingredients. The Panel noted gaps in the available safety data for some of the alkyl sultaines in this safety assessment; the available data on some of the ingredients are sufficient, however, and can be read across to support the safety of other members of the group. The Panel concluded that these alkyl sultaines are safe in cosmetics in the present practices of use and concentration described in this safety assessment.

Keywords: Capryl Sultaine; Cetyl/Lauryl/Myristyl Hydroxysultaine; Cocamidopropyl Hydroxysultaine; Coco-Hydroxysultaine; Coco-Sultaine; Cosmetics; Erucamidopropyl Hydroxysultaine; Lauramidopropyl Hydroxysultaine; Lauryl Hydroxysultaine; Lauryl Sultaine; Myristamidopropyl Hydroxysultaine; Myristyl Sultaine; Oleamidopropyl Hydroxysultaine; Safety; Tallowamidopropyl Hydroxysultaine.

MeSH terms

  • Consumer Product Safety*
  • Cosmetics* / toxicity
  • Risk Assessment
  • Skin
  • Surface-Active Agents

Substances

  • Cosmetics
  • Surface-Active Agents