A technique for introducing broad-spectrum topical antibiotics during open reduction and internal fixation of acetabular fractures

Eur J Orthop Surg Traumatol. 2024 Apr;34(3):1701-1705. doi: 10.1007/s00590-023-03789-3. Epub 2023 Dec 6.

Abstract

Postoperative surgical site infections remain a significant and prevalent complication after open reduction and internal fixation of acetabular fractures. Local antibiotics have been shown to decrease risk of postoperative infection, although recent evidence is conflicting. We provide a consistent and replicable technique for delivering intraoperative broad-spectrum antibiotics in the form of a putty applied directly to surgical implants. With this technique, systemic levels of those antibiotics remain safe and stable.

Keywords: Infection; Local antibiotics; Orthopedic trauma; Tobramycin; Vancomycin.

MeSH terms

  • Acetabulum / surgery
  • Anti-Bacterial Agents* / therapeutic use
  • Fracture Fixation, Internal / adverse effects
  • Fracture Fixation, Internal / methods
  • Hip Fractures* / surgery
  • Humans
  • Retrospective Studies
  • Surgical Wound Infection / etiology
  • Surgical Wound Infection / prevention & control
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents