Cancer Treat Rep. 1987 Feb;71(2):137-40.

Prolonged unmaintained remission after intensive consolidation therapy in adult acute nonlymphocytic leukemia.

Cassileth PA, Begg CB, Silber R, Spiers A, Burkart PT, Scharfman W, Knospe WH, Bennett JM, Mazza JJ, Oken MM, et al.

Abstract

Thirty-five adults with acute nonlymphocytic leukemia who were in complete remission after initial induction therapy received a single course of high-dose cytarabine and amsacrine as consolidation therapy. No further therapy was administered. Despite substantial toxicity, the median duration of disease-free survival was 12 months, and 30% of patients are projected to be alive in continuous complete remission at 3 years. A single course of intensive postremission chemotherapy provides long-term disease-free survival in the absence of any further treatment.

PMID:: 3802110; [PubMed - indexed for MEDLINE]

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Cancer Treat Rep. 1987 Feb ;71(2):137-40.

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Prolonged unmaintained remission after intensive consolidation therapy in adult acute nonlymphocytic leukemia.

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