Although the 1-hour 50 gm blood glucose screening test is an effective way of detecting diabetes in pregnancy, the taste of available glucose drinks often creates gastrointestinal symptoms and leads to refusal of the patient to be tested. The efficacy of a virtually tasteless glucose polymer in testing carbohydrate tolerance in pregnancy was determined. Sixty-one pregnant patients undergoing screening for gestational diabetes underwent a 1-hour carbohydrate tolerance test of both glucose and a glucose polymer within 3 days of each other. Analysis of the data revealed a high degree of agreement between the results of the 1-hour carbohydrate tolerance test (kappa = 0.62, p less than 0.0001). These data suggest that glucose polymer can be used effectively in screening for gestational diabetes.