Long-term Cardiovascular Disease After Adverse Pregnancy Outcomes

J Clin Endocrinol Metab. 2024 Feb 20;109(3):e883-e891. doi: 10.1210/clinem/dgad600.

Abstract

Cardiovascular disease (CVD) is the leading cause of death among women. Adverse pregnancy outcomes (APOs) are cardiovascular risk factors that are unique to women and include gestational diabetes (GDM) and preeclampsia. While these risk factors emerge during the reproductive years and allow for early risk reduction counseling, they are often overlooked and not elicited by providers. This mini-review focuses primarily on GDM and preeclampsia, their relationship with CVD, mechanisms by which these conditions lead to CVD, and management, pharmacological and nonpharmacological, for the clinician who is caring for a woman with a history of an APO.

Keywords: adverse pregnancy outcomes; cardiovascular disease; gestational diabetes; preeclampsia.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases* / epidemiology
  • Cardiovascular Diseases* / etiology
  • Diabetes, Gestational*
  • Female
  • Humans
  • Pre-Eclampsia* / epidemiology
  • Pregnancy
  • Pregnancy Outcome / epidemiology
  • Risk Factors