Twin pregnancy with incomplete hydatidiform mole and coexistent normal live fetus: A case report and review of the literature

Medicine (Baltimore). 2023 Nov 3;102(44):e35072. doi: 10.1097/MD.0000000000035072.

Abstract

Rationale: A pregnancy with incomplete mole is very rare case. Hydatidiform mole (HM) with live fetus is associated with a risk of a wide variety to maternal and fetal complications. The incidence of a normal live fetus and an incomplete mole such as the case we describe is extremely rare.

Patient concern: We report a case of multiparous 34-year-old at Culiacan Mexico woman with incomplete mole coexisting with normal fetus, pregnant 35.3 weeks who presented anemia grade II.

Diagnosis: The initial diagnosis of the mole was by ultrasound.

Interventions: KERR-type cesarean section and bilateral tubal occlusion. The newborn was morphologically normal, and she did not require intervention or treatment.

Outcomes: The newborn was feminine, morphologically normal, weighing 2380 g and 47 cm, APGAR score 8 to 9, delivered prematurely, and there was a large placental plate. The blood loss on surgery was estimated at 1000 mL. Histopathology report of an incomplete hydatidiform mole, negative for malignancy. Histopathology diagnostic was confirmed by immunohistochemistry staining for p57KIP2.

Lessons: Although the incidence of this pregnancy is very rare, early recognition, diagnosis and divulge of the cases of medical community is very important for patient care.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Adult
  • Cesarean Section
  • Female
  • Fetus / pathology
  • Humans
  • Hydatidiform Mole* / diagnosis
  • Infant, Newborn
  • Placenta / pathology
  • Pregnancy
  • Pregnancy, Twin
  • Uterine Neoplasms* / pathology