-
Chromosome 1 localization of the human alpha-L-fucosidase structural gene with a homologous site on chromosome 2.
Two cDNA clones coding for human alpha-L-fucosidase, one from the coding region and the other primarily from the 3' untranslated region, were used to map the location of the alpha-L-fucosidase gene. Southern filter analysis of somatic cell hybrid lines mapped the structural gene to the short arm of human chromosome 1, and in situ hybridization to chromosomes of human leukocytes further localized the homologous area to the 1p36.1----p34.1 region, with the most likely location being the distal region of 1p34. Further Southern filter analysis detected a second site of homology on chromosome 2. This alpha-L-fucosidase-like site has been designated FUCA1L.
PMID: 3780313 [PubMed - indexed for MEDLINE]
-
Cited by 8 PubMed Central articles
-
The genes encoding the peripheral cannabinoid receptor and alpha-L-fucosidase are located near a newly identified common virus integration site, Evi11.
Valk PJ, Hol S, Vankan Y, Ihle JN, Askew D, Jenkins NA, Gilbert DJ, Copeland NG, de Both NJ, Löwenberg B, et al.
J Virol. 1997 Sep; 71(9):6796-804.
[J Virol. 1997]
-
Fucosidosis: genetic and biochemical analysis of eight cases.
Cragg H, Williamson M, Young E, O'Brien J, Alhadeff J, Fang-Kircher S, Paschke E, Winchester B.
J Med Genet. 1997 Feb; 34(2):105-10.
[J Med Genet. 1997]
-
A 5' splice site mutation in fucosidosis.
Williamson M, Cragg H, Grant J, Kretz K, O'Brien J, Willems PJ, Young E, Winchester B.
J Med Genet. 1993 Mar; 30(3):218-23.
[J Med Genet. 1993]
- » See all...