Brain Res. 1986 Sep 10;382(1):199-203.

Ibotenic acid lesions in the medial geniculate region prevent the acquisition of differential Pavlovian conditioning of bradycardia to acoustic stimuli in rabbits.

Jarrell TW, Romanski LM, Gentile CG, McCabe PM, Schneiderman N.

Abstract

The present study examined the effect of ibotenic acid lesions in the medial portion of the medial geniculate nucleus (mMGN) on differential heart rate (HR) conditioning to acoustic stimuli in rabbits. Lesions in mMGN prevented the acquisition of differential HR conditioned responses but not bradycardiac responses to the conditioned stimuli. The data suggest that cells in this region play an important role in the discriminative component of HR conditioning.

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Ibotenic acid lesions in the medial geniculate region prevent the acquisition of differential Pavlovian conditioning of bradycardia to acoustic stimuli in rabbits.

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