Antibiotiki. 1979 May;24(5):331-6.

[Comparative experimental study of cyclacillin and ampicillin].

[Article in Russian]

Rudzit EA, Iakovlev VP, Zinchenko TA, Kulikova DA, Lisitsa LI.

Abstract

Cyclacillin was compared with ampicillin by its bacteriostatic efficiency in vitro, chemotherapeutic efficiency in experimental infections of mice and rats and pharmacokinetic characteristics. It was found that cyclacillin was not superior to ampicillin by its antibacterial action. By a number of characteristics it was even significantly inferior. The pharmacokinetic advantages of cyclacillin were not considered significant.

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[Comparative experimental study of cyclacillin and ampicillin].

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