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    Ann Neurol. 1979 Apr;5(4):389-90.

    Thrombocytopenia associated with sodium valproate treatment.

    Abstract

    The administration of sodium valproate to 30 patients in daily doses of 1,200 to 3,000 mg was associated with a significant reduction of the platelet count. Thrombocytopenia without any concomitant bleeding abnormalities occurred in 10 of the patients. Platelet counts returned to baseline levels after withdrawal of the drug.

    PMID:
    375808
    [PubMed - indexed for MEDLINE]

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