Nephron. 1979;23(2-3):61-71.

Kallikrein, kininogen and kinins in control of blood pressure.

Abstract

Plasma kallikrein releases bradykinin when activated by gram-negative septicemia or irreversible hemorrhagic shock. Pancreatitis releases glandular kallikrein causing hypotension and increased vascular permeability. Bradykinin in the brain produces hypertension. Renal kallikrein is released by high arterial pressure, vasodilators, low doses of noradrenaline, angiotensin II, mineralocorticoids and rapid volume expansion. It has a biphasic relation to sodium excretion. In essential hypertension, kallikrein release into the blood and urine is low and facilitates hypertension. High renin in Bartter's syndrome is balanced by high PGE and kallikrein without hypertension.

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Review [Renal kallikrein-kinin system and control of blood pressure (author's transl)]. [Klin Wochenschr. 1979]
Review [Renal kallikrein-kinin system and control of blood pressure (author's transl)].
Distler A, Wolff HP. Klin Wochenschr. 1979 Oct 1; 57(19):1037-45.
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Rodriguez-Portales JA, Lopez-Moreno JM, Mahana D. Hypertension. 1985 Nov-Dec; 7(6 Pt 1):1017-22.
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Review The renal kallikrein-kinin system in human and in experimental hypertension.
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Cited by 3 PubMed Central articles

Urinary kallikrein in the rat: stimulation with angiotensin infusion but depression with increasing sodium concentration. [J Physiol. 1994]
Urinary kallikrein in the rat: stimulation with angiotensin infusion but depression with increasing sodium concentration.
Mills IH, Lee G, Brownlee AA. J Physiol. 1994 Dec 1; 481 ( Pt 2):425-37.
The plasma kallikrein kinin system in severely ill and traumatised patients. [Arch Emerg Med. 1984]
The plasma kallikrein kinin system in severely ill and traumatised patients.
Cumming AD, Robertson CE, Jeffrey SS, Robson JS, Ledingham IM. Arch Emerg Med. 1984 Sep; 1(3):135-42.
Receptors for bradykinin in intact cultured human fibroblasts. Identification and characterization by direct binding study. [J Clin Invest. 1983]
Receptors for bradykinin in intact cultured human fibroblasts. Identification and characterization by direct binding study.
Roscher AA, Manganiello VC, Jelsema CL, Moss J. J Clin Invest. 1983 Aug; 72(2):626-35.

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Kallikrein, kininogen and kinins in control of blood pressure.

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