Regression and stabilization of atherogenic plaques

Jairo Aldana-Bitar; Deepak L Bhatt; Matthew J Budoff

doi:10.1016/j.tcm.2023.07.002

Regression and stabilization of atherogenic plaques

Trends Cardiovasc Med. 2023 Jul 24:S1050-1738(23)00063-4. doi: 10.1016/j.tcm.2023.07.002. Online ahead of print.

Authors

Jairo Aldana-Bitar¹, Deepak L Bhatt², Matthew J Budoff³

Affiliations

¹ The Lundquist Institute at Harbor-UCLA Medical Center, Division of Cardiology, Los Angeles, CA, USA.
² Mount Sinai Heart, Dr. Valentin Fuster Professor of Medicine, Icahn School of Medicine at Mount Sinai Health System, New York, NY, USA.
³ The Lundquist Institute at Harbor-UCLA Medical Center, Division of Cardiology, Los Angeles, CA, USA. Electronic address: mbudoff@labiomed.org.

PMID: 37494987
DOI: 10.1016/j.tcm.2023.07.002

Abstract

Atherosclerotic plaque assessment has become a crucial element in the examination of cardiovascular diseases. Plaque may exhibit progression and could become unstable if not treated, making plaque regression and stabilization among the most important goals of any cardiovascular intervention in cardiovascular medicine. In this review, we explore the current understanding of plaque regression and stabilization, discuss imaging and measurement techniques, and examine the evidence for pharmacological interventions and other interventions aimed at addressing this condition.

Keywords: Atherosclerosis; Cardiac computed tomography; IVUS; Plaque; Regression; Stabilization.

Publication types

Review