Unilateral keratitis secondary to Leishmania spp. infection in a horse: Clinical signs and successful topical therapy

Vet Ophthalmol. 2024 Jan;27(1):86-89. doi: 10.1111/vop.13134. Epub 2023 Jul 25.

Abstract

Dermatological clinical signs have been seldom reported in the literature secondary to equine leishmaniasis. This case depicts the clinical signs, treatment, and outcome of a young horse with a pink, elevated lesion on the ventromedial quadrant of the cornea. A corneal cytology was performed and revealed the presence of leishmania amastigotes reaching the diagnosis of keratitis secondary to leishmania. Surgical resection was recommended but the owner declined the procedure, and the lesion was treated with a topical antimonial for 6 weeks. The lesion reduced remarkably during the first weeks of treatment. The patient had not shown recurrence of the lesion for 2 years since the treatment was started. Leishmania spp. can be responsible for ocular surface abnormalities such as keratitis. Corneal cytology is an inexpensive diagnostic method that should be considered when ocular surface abnormalities are identified in horses in endemic areas.

Keywords: Leishmania; amastigotes; antimonials; cytology; equine; keratitis.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Cornea / pathology
  • Horse Diseases* / diagnosis
  • Horse Diseases* / drug therapy
  • Horse Diseases* / pathology
  • Horses
  • Keratitis* / diagnosis
  • Keratitis* / drug therapy
  • Keratitis* / veterinary
  • Leishmania*
  • Leishmaniasis* / diagnosis
  • Leishmaniasis* / drug therapy
  • Leishmaniasis* / veterinary