Response to "Plant-based diets and postprandial hyperkalemia"

Nutr Rev. 2024 Mar 11;82(4):572-577. doi: 10.1093/nutrit/nuad068.

Abstract

Diet therapy for hyperkalemia in people with chronic kidney disease (CKD) has shifted considerably in recent years with the observations that reported potassium intake is weakly, or not at all, associated with plasma potassium levels in this population. One of the lingering debates is whether dietary potassium presents a risk of hyperkalemia in the postprandial state. Although there is general agreement about the need for additional research, the commentary by Varshney et al contends that the available research sufficiently demonstrates that high-potassium plant foods do not pose a risk of postprandial hyperkalemia. Others argue that this remains unsettled science. Although the traditional approach of providing people with CKD lists of high-potassium foods to limit or avoid may be unnecessary, those at high risk of hyperkalemia should be encouraged to consume balanced meals and control portions, at least until some of the key research gaps in this area are resolved. This editorial critiques the analyses offered by Varshney et al and explains the rationale for a more cautious approach to care.

Keywords: chronic kidney disease; dietary potassium; hyperkalemia; kidney failure; plant-rich foods; postprandial.

MeSH terms

  • Diet
  • Diet, Plant-Based
  • Humans
  • Hyperkalemia* / etiology
  • Hyperkalemia* / prevention & control
  • Potassium
  • Renal Insufficiency, Chronic* / complications

Substances

  • Potassium