Clavamycins, new clavam antibiotics from two variants of Streptomyces hygroscopicus. I. Taxonomy of the producing organisms, fermentation, and biological activities

J Antibiot (Tokyo). 1986 Apr;39(4):510-5. doi: 10.7164/antibiotics.39.510.

Abstract

In a selective screening for antifungal metabolites, six new clavam antibiotics, clavamycins A, B, C, D, E and F, have been detected from two variants of Streptomyces hygroscopicus NRRL 15846 and NRRL 15879.

MeSH terms

  • Antifungal Agents / biosynthesis*
  • Antifungal Agents / pharmacology
  • Candida / drug effects
  • Fermentation
  • Peptides / pharmacology
  • Streptomyces / classification
  • Streptomyces / metabolism*

Substances

  • Antifungal Agents
  • Peptides