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    J Hyg (Lond). 1986 Apr;96(2):143-51.

    The protection of infant mice from colonization with Campylobacter jejuni by vaccination of the dams.

    Abstract

    Intraperitoneal vaccination of female mice, before mating, with a whole cell, heat-killed (62 degrees C) vaccine of Campylobacter jejuni allowed the mother to confer immunity to her young, challenged orally 4-6 days after birth with the homologous strain. There was no protection against a strain of another serotype. Heating the vaccine to 100 degrees C destroyed its protective properties. A vaccine prepared from an aflagellate variant of the original strain was as protective as the original vaccine against challenge with the flagellated strain. Anti-flagellar serum antibody titres of the dams did not correlate with protection of their young.

    PMID:
    3701036
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC2129651
    Free PMC Article

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