The Osteogenic Role of Biomaterials Combined with Human-Derived Dental Stem Cells in Bone Tissue Regeneration

Tissue Eng Regen Med. 2023 Apr;20(2):251-270. doi: 10.1007/s13770-022-00514-9. Epub 2023 Feb 20.

Abstract

The use of stem cells in regenerative medicine had great potential for clinical applications. However, cell delivery strategies have critical importance in stimulating the differentiation of stem cells and enhancing their potential to regenerate damaged tissues. Different strategies have been used to investigate the osteogenic potential of dental stem cells in conjunction with biomaterials through in vitro and in vivo studies. Osteogenesis has a broad implication in regenerative medicine, particularly for maxillofacial defects. This review summarizes some of the most recent developments in the field of tissue engineering using dental stem cells.

Keywords: Dental biomaterials; Dental stem cells; Osteogenic differentiation.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biocompatible Materials* / pharmacology
  • Bone Regeneration
  • Bone and Bones
  • Humans
  • Osteogenesis*
  • Stem Cells

Substances

  • Biocompatible Materials