Low Skeletal Muscle Index Adjusted for Body Mass Index Is an Independent Risk Factor for Inflammatory Bowel Disease Surgical Complications

Matthew Berger; Akihiro Yamada; Yuga Komaki; Fukiko Komaki; Russell D Cohen; Sushila Dalal; Roger D Hurst; Neil Hyman; Joel Pekow; Benjamin D Shogan; Konstantin Umanskiy; David T Rubin; Atsushi Sakuraba; Dejan Micic

doi:10.1093/crocol/otaa064

Low Skeletal Muscle Index Adjusted for Body Mass Index Is an Independent Risk Factor for Inflammatory Bowel Disease Surgical Complications

Crohns Colitis 360. 2020 Aug 1;2(3):otaa064. doi: 10.1093/crocol/otaa064. eCollection 2020 Jul.

Authors

Affiliations

¹ Section of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, University of Chicago Medicine, Chicago, Illinois, USA.
² Section of Gastroenterology, Department of Internal Medicine, Toho University Sakura Medical Center, Chiba, Japan.
³ Digestive and Lifestyle Diseases, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
⁴ Section of Colon and Rectal Surgery, Department of Surgery, University of Chicago Medicine, Chicago, Illinois, USA.

Abstract

Background: This study aims to evaluate sarcopenia defined by skeletal muscle index (SMI) with cutoffs adjusted for sex and body mass index as a predictive marker for postoperative outcomes among individuals with inflammatory bowel disease.

Methods: The SMI was measured using the cross-sectional computed tomography images at the lumbar spine. Multivariate logistic regression was performed to identify independent risk factors of postoperative complications.

Results: Ninety-one patients were included in the study. In multivariate analysis, sarcopenia (odds ratio = 5.37; confidence interval: 1.04-27.6) was predictive of infectious postoperative complications.

Conclusions: Sarcopenia as defined by the SMI is a predictor for 30-day postoperative infection complications in inflammatory bowel disease surgeries.

Keywords: inflammatory bowel disease; postoperative complications; sarcopenia.