TASL, TADE, and DAROC consensus for the screening and management of hepatitis C in patients with diabetes

J Formos Med Assoc. 2023 Mar;122(3):202-220. doi: 10.1016/j.jfma.2023.01.011. Epub 2023 Feb 6.

Abstract

Diabetes mellitus (DM) and hepatitis C virus (HCV) infection are prevalent diseases globally and emerging evidence demonstrates the bidirectional association between the two diseases. Direct-acting antivirals (DAAs) for HCV have a high treatment success rate and can significantly reduce the risks of short and long-term complications of HCV infection. However, despite the evidence of the association between diabetes and HCV and the benefits of anti-HCV treatment, previously published guidelines did not focus on the universal HCV screening for patients with diabetes and their subsequent management once confirmed as having HCV viremia. Nonetheless, screening for HCV among patients with diabetes will contribute to the eradication of HCV infection. Thus, the three major Taiwan medical associations of diabetes and liver diseases endorsed a total of 14 experts in the fields of gastroenterology, hepatology, diabetology, and epidemiology to convene and formulate a consensus statement on HCV screening and management among patients with diabetes. Based on recent studies and guidelines as well as from real-world clinical experiences, the Taiwan experts reached a consensus that provides a straightforward approach to HCV screening, treatment, and monitoring of patients with diabetes.

Keywords: Consensus statement; Diabetes mellitus; Direct-acting antivirals; Hepatitis C virus.

Publication types

  • Practice Guideline

MeSH terms

  • Antiviral Agents / therapeutic use
  • Diabetes Mellitus* / drug therapy
  • Hepacivirus
  • Hepatitis C* / drug therapy
  • Hepatitis C, Chronic* / drug therapy
  • Humans

Substances

  • Antiviral Agents