Send to:

Choose Destination
See comment in PubMed Commons below
Am J Clin Nutr. 1987 Nov;46(5):763-71.

Zinc and pregnancy outcome.

Author information

  • 1Department of Nutritional Sciences, University of California, Berkeley 94720.


Total zinc needs during the last half of human pregnancy may be approximately 2.6 mg absorbed Zn/d. Adaptations in Zn utilization during pregnancy may help meet those needs. Possible adaptations include an increase in Zn absorption, reduced endogenous Zn loss, redistribution of tissue Zn, and an efficient maternal-fetal Zn transfer. A decline in circulating Zn concentration begins early in pregnancy and continues to term. The effect of gestational stage on circulating Zn should be incorporated into standards for serum Zn of pregnant women. Low maternal serum Zn levels have been associated with pregnancy-induced hypertension, abnormal parturition, and congenital anomalies. In studies done to date, Zn supplementation of 15-45 mg/d failed to improve pregnancy outcome except for a possible reduction in the incidence of a dysfunctional labor pattern. The relationship between Zn status and pregnancy outcome remains an open question.

[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk