Effect of bariatric surgery on carotid intima-media thickness: A meta-analysis based on observational studies

Hui Zhou; Yangli Jin; Senjie Dai; Chenglong Dai; Xia Ye

doi:10.3389/fsurg.2022.1068681

Effect of bariatric surgery on carotid intima-media thickness: A meta-analysis based on observational studies

Front Surg. 2023 Jan 10:9:1068681. doi: 10.3389/fsurg.2022.1068681. eCollection 2022.

Authors

Hui Zhou¹, Yangli Jin², Senjie Dai³, Chenglong Dai⁴, Xia Ye⁵

Affiliations

¹ Department of Ultrasound, The Affiliated Hospital of Ningbo University, LiHuiLi Hospital, Ningbo, China.
² Department of Ultrasound, Ningbo Yinzhou No. 2 Hospital, Ningbo, China.
³ The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.
⁴ School of Medical Imaging, Hangzhou Medical College, Hangzhou, China.
⁵ General Family Medicine, Ningbo Yinzhou No. 2 Hospital, Yinzhou district, ningbo, China.

Abstract

Objective: This meta-analysis aimed to investigate the effect of bariatric surgery on CIMT in people with obesity.

Methods: PubMed, Web of Science, Embase, and the Cochrane Library were searched for observational studies assessing the effect of bariatric surgery on CIMT from inception to August 2022. Mean difference (MD) and 95% confidence intervals were calculated to assess CIMT.

Results: A total of 23 studies, including 1,349 participants, were eligible to participate in this meta-analysis. The results revealed that CIMT was significantly decreased at 6 months, 12 months, and more than 18 months after bariatric surgery compared with baseline (6 months: MD = 0.09; P < 0.01; 12 months: MD = 0.12; P < 0.01; more than 18 months: MD = 0.14; P = 0.02). Meanwhile, laparoscopic Roux-en-Y gastric bypass (LRYGB) seemed to be more effective than laparoscopic sleeve gastrectomy (LSG) in lowering CIMT in terms of the type of surgery (LSG: MD = 0.11; P < 0.01; LRYGB: MD = 0.14; P < 0.01). Lastly, the benefits of bariatric surgery on CIMT was independent of gender (Male: MD = 0.06; P = 0.04; Female: MD = 0.08; P = 0.03).

Conclusions: Bariatric surgery is consistently effective in reducing CIMT in people with obesity.

Keywords: bariatric surgery; carotid intima-Media thickness; meta-analysis; obesity; weight loss.

Publication types

Review

Grants and funding

This study was supported by the Natural Science Foundation of Ningbo, China (project No. 2018A610398), the Medical Health Science and Technology Project of Zhejiang Provincial Health Commission, China, (project No. 2022KY343), and the Science and Technology Program for Public wellbeing of Ningbo, China (project No. 2022AS069).