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Arch Toxicol. 1987 Aug;60(6):467-9.

The effect of a lipid suspension on amitriptyline disposition.

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  • 1Poisons Unit, Guy's Hospital, London, UK.

Abstract

A 5-h infusion of a lipid suspension or saline was given on separate occasions to four healthy volunteers taking amitriptyline. Mean plasma levels of amitriptyline plus nortriptyline were 14% higher at the end of the lipid infusion but the difference was not statistically significant. Infusion of a lipid suspension is unlikely to materially affect the severity of amitriptyline intoxication.

PMID:
3662823
[PubMed - indexed for MEDLINE]
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