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    Ann Emerg Med. 1987 Oct;16(10):1162-4.

    Tagamet-induced acute dystonia.

    Romisher S, Felter R, Dougherty J.

    Department of Emergency Medicine, Akron General Hospital, Ohio.

    A 20-year-old woman presented with an apparent acute dystonic reaction after only five doses of cimetidine (Tagamet). The patient was on no other medications with the exception of oral contraceptives. Emergency administration of IV diphenhydramine HCL brought rapid reversal of this acute dystonic reaction without any neurological sequelae. To our knowledge, this is the first reported case of an acute dystonic reaction associated with cimetidine.

    PMID: 3662164 [PubMed - indexed for MEDLINE]

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    Patient drug information

    • Cimetidine (Tagamet®, Tagamet® HB, Tagamet® Tiltab®)

      Cimetidine is used to treat ulcers; gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and injury of the food pipe (esophagus); and conditions where the s...

    • Diphenhydramine (AllerMax®, AllerMax® Caplets®, Benadryl®, ...)

      Diphenhydramine is used to relieve red, irritated, itchy, watery eyes; sneezing; and runny nose caused by hay fever, allergies, or the common cold. Diphenhydramine is also used to relieve cough caused by minor throat or ...

    • Source: AHFS Consumer Medication Information

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