Steroids and related products. LIV. The synthesis of 11-oxa steroids. VI. The synthesis of 11-oxatestosterone

Steroids. 1986 Jul-Aug;48(1-2):47-53. doi: 10.1016/0039-128x(86)90040-1.

Abstract

The synthesis of 11-oxatestosterone from 11-oxa-5 alpha-androstane-3,17-dione, which is available from hecogenin, is described. The product shows, in comparison with the natural hormone, diminished androgenic and anabolic activities.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Anabolic Agents / chemical synthesis
  • Animals
  • Chemical Phenomena
  • Chemistry
  • Male
  • Methods
  • Rats
  • Steroids, Heterocyclic / chemical synthesis*
  • Steroids, Heterocyclic / pharmacology
  • Testosterone / analogs & derivatives*
  • Testosterone / chemical synthesis
  • Testosterone / pharmacology
  • Testosterone Congeners / chemical synthesis

Substances

  • Anabolic Agents
  • Steroids, Heterocyclic
  • Testosterone Congeners
  • 11-oxatestosterone
  • Testosterone