Abstract
The synthesis of 11-oxatestosterone from 11-oxa-5 alpha-androstane-3,17-dione, which is available from hecogenin, is described. The product shows, in comparison with the natural hormone, diminished androgenic and anabolic activities.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Anabolic Agents / chemical synthesis
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Animals
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Chemical Phenomena
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Chemistry
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Male
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Methods
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Rats
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Steroids, Heterocyclic / chemical synthesis*
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Steroids, Heterocyclic / pharmacology
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Testosterone / analogs & derivatives*
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Testosterone / chemical synthesis
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Testosterone / pharmacology
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Testosterone Congeners / chemical synthesis
Substances
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Anabolic Agents
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Steroids, Heterocyclic
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Testosterone Congeners
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11-oxatestosterone
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Testosterone