Video-assisted thoracoscopic sympathectomy for Harlequin syndrome

Eur J Cardiothorac Surg. 2023 Feb 3;63(2):ezac577. doi: 10.1093/ejcts/ezac577.

Abstract

Harlequin syndrome is an exceedingly rare condition, characterized by unilateral facial flushing and hyperhidrosis. Postulated to be dysregulated sympathetic nervous system stimulation of the dermal vasculature and blood vessels of the face. There is no clear unifying pathological cause. Due to its heterogeneity and rarity, very little is known about the treatment of it. Hereafter, we describe our experience in successfully curing right-sided Harlequin syndrome through video-assisted thoracoscopic sympathectomy.

Keywords: Harlequin syndrome; Treatment; Video-assisted thoracic surgery.

MeSH terms

  • Autonomic Nervous System Diseases* / surgery
  • Humans
  • Hyperhidrosis* / surgery
  • Hypohidrosis* / surgery
  • Sympathectomy
  • Thoracic Surgery, Video-Assisted
  • Treatment Outcome

Supplementary concepts

  • Harlequin syndrome