The research status and progress of core outcome set in oral health

Yansong Song; Ling Ren; Jiaxin Liu; Xin Zeng; Qianming Chen; Hongxia Dan

doi:10.1016/j.oooo.2022.11.002

The research status and progress of core outcome set in oral health

Oral Surg Oral Med Oral Pathol Oral Radiol. 2023 Feb;135(2):249-256. doi: 10.1016/j.oooo.2022.11.002. Epub 2022 Nov 11.

Authors

Yansong Song¹, Ling Ren², Jiaxin Liu³, Xin Zeng⁴, Qianming Chen⁵, Hongxia Dan⁶

Affiliations

¹ State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Research Unit of Oral Carcinogenesis and Management, Chinese Academy of Medical Sciences, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China. Electronic address: 15390013468@163.com.
² State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Research Unit of Oral Carcinogenesis and Management, Chinese Academy of Medical Sciences, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China. Electronic address: 1418267744@qq.com.
³ State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Research Unit of Oral Carcinogenesis and Management, Chinese Academy of Medical Sciences, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China. Electronic address: 327414092@qq.com.
⁴ State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Research Unit of Oral Carcinogenesis and Management, Chinese Academy of Medical Sciences, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China. Electronic address: zengxin22@163.com.
⁵ State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Research Unit of Oral Carcinogenesis and Management, Chinese Academy of Medical Sciences, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China; Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, China. Electronic address: qmchen@scu.edu.cn.
⁶ State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Research Unit of Oral Carcinogenesis and Management, Chinese Academy of Medical Sciences, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China. Electronic address: Hxdan@foxmail.com.

PMID: 36528484
DOI: 10.1016/j.oooo.2022.11.002

Abstract

The core outcome set (COS) refers to the minimum set of outcomes that should be reported by all clinical trials in a particular health field. The use of COS in clinical studies can reduce the heterogeneity caused by using different outcomes across different clinical studies, facilitate the systematic review of different clinical studies on the same topic, reduce selective reporting bias, and increase the utility of clinical studies. The importance of COS in oral health has recently been recognized. This review summarizes the history, necessity, and key methodological points of COS development, with emphasis on the research status and existing problems in COS development, in the field of oral health.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Consensus
Delphi Technique
Endpoint Determination
Humans
Oral Health*
Outcome Assessment, Health Care
Research Design*
Treatment Outcome